Magnetic Particle Imaging

Please follow the links below for more detailed information about each project we are currently pursuing.

Single-Sided Magnetic Particle Imaging
Magnetic Particle Spectroscopy
Model-Based Reconstruction
Simulation Studies
Contrast Agents
Clinical Application

The Institute of Medical Engineering is organizing an International Workshop on MPI at March 18-19, 2010.

Pressemitteilung Uni Lübeck
Onside, 2007
HL-Live, 27.02.2008
BMBF, October 2008
HL-Live, 27.10.2008
Analytica World, 29.10.2008
BMBF Gesundheitsforschung, 2009
Handelsblatt, 27.05.2009
ZEIT, 27.07.2009 Herzschlag in Echtzeit
HL-Live, 17.09.2009 Internationale Innovationspreise für die Uni Lübeck
Ärzte Zeitung, 16.10.2009 Bessere Bildgebung mit Eisen-Nanopartikeln
Lübecker Nachrichten, 10.03.2010 Großer Einblick durch kleine Teilchen
IDW, 29.03.2010 Magnetic Particle Imaging: Aufbruchstimmung wie zuletzt bei der Entwicklung der Magnetresonanz-Tomographie
Anchener Nachrichten, 30.07.2010 Neues Aufnahmeverfahren: Eisen macht das rasende Herz sichtbar

Other Media

Interview on Science TV, 2009
Interview on Deutschlandfunk (German Radio), 19.03.2010

The Institute of Medical Engineering won the BMBF Innovation Award 2008.

The developement in the field of MPS is financially supported by the innovation foundation of the state of Schleswig-Holstein.

The development of the Single-Sided MPI device is financially supported by the Federal Ministry of Education and Research (BMBF).

Philips Research Hamburg
Clinics of Gynecology (Prof. Dr. Klaus Diedrich)
Clinics of Radiology and Nuclear Medicine (Prof. Dr. Jörg Barkhausen)
Clinics of Otolaryngology (Prof. Dr. Barbara Wollenberg)

Articles

T. Knopp, M. Erbe , T. F. Sattel, S. Biederer, T. M. Buzug: Generation of a static magnetic field-free line using two Maxwell coil pairs, Appl. Phys. Lett., 2010, 97, p.092505-1-092505-3

T. Knopp, M. Erbe, S. Biederer, T.F. Sattel, T.M. Buzug: Efficient generation of a magnetic field-free line, Medical Physics, 2010, 37, 7, p.3538-3540

T. Knopp, J. Rahmer , T. F. Sattel , S. Biederer, J. Weizenecker, B. Gleich, J. Borgert, T. M. Buzug: Weighted iterative reconstruction for magnetic particle imaging, Physics in Medicine and Biology, 2010, 55, p.1577–1589

T. Knopp, S. Biederer, T. F. Sattel, J. Rahmer, J. Weizenecker, B. Gleich, J. Borgert, T. M. Buzug: 2D Model-based reconstruction for magnetic particle imaging, Medical Physics, 2010, 37, p.485-491

T. Knopp, T. Sattel, S. Biederer, J. Rahmer, J. Weizenecker, B. Gleich, J. Borgert, T.M. Buzug: Model-Based Reconstruction for Magnetic Particle Imaging, IEEE Trans. Med. Imag., 2010, 29, 1, p.12-18

T. Knopp, T. F. Sattel, S. Biederer T. M. Buzug: Field-Free line formation in a magnetic field, Journal of Physics A: Mathematical and Theoretical., 2010, 43, 1, p.9pp

S. Biederer, T. Knopp, T. F. Sattel, K. Lüdtke-Buzug, B. Gleich J. Weizenecker J. Borgert, T. M. Buzug: Magnetization Response Spectroscopy of Superparamagnetic Nanoparticles for Magnetic Particle Imaging, Journal of Physics D: Applied Physics, 2009, 42, 20, p.7pp

T. Knopp, S. Biederer, T. Sattel, J. Weizenecker, B. Gleich, J. Borgert, T.M. Buzug: Trajectory Analysis for Magnetic Particle Imaging, Physics in Medicine and Biology, 2009, 54, 2, p.385-397

T. Sattel, T. Knopp, S. Biederer, B. Gleich, J. Weizenecker, J. Borgert, T. M. Buzug: Single-Sided Device for Magnetic Particle Imaging, Journal of Physics D: Applied Physics, 2009, 42, 2, p.1-5

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Books

T. M. Buzug, J. Borgert, T. Knopp, S. Biederer, T. F. Sattel, M. Erbe, K. Lüdtke-Buzug (Eds.): Magnetic Nanoparticles: Particle Science, Imaging Technology, and Clinical Applications, World Scientific Publishing Company, 2010
T. M. Buzug, S. Biederer, J. Borgert, M. Erbe, T. Knopp, K. Lüdtke-Buzug, T. F. Sattel (Eds.): 1st International Workshop on Magnetic Particle Imaging (IWMPI 2010) - Book of Abstracts, Verlags- und Druckhaus Max Schmidt-Römhild KG, 2010, Lübeck

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Inproceedings

M. Erbe, T. Knopp, S. Biederer, T. F. Sattel, T. M. Buzug: Experimentelle Erzeugung einer magnetischen feldfreien Linie für die Anwendung in Magnetic Particle Imaging, to be published in: 44. Jahrestagung der Deutschen Gesellschaft für Biomedizinische Technik im VDE - BMT 2010, 2010, Rostock, Germany

S. Biederer, S. Kren, T.F. Sattel, M. Erbe, T.Knopp, K. Lüdtke-Buzug, T.M. Buzug: Ein magnetisches Partikel-Spektrometer zur Messung der Magnetisierung von Nanopartikeln unter der Verwendung von AC- und DC-Feldern, to be published in: 44. Jahrestagung der Deutschen Gesellschaft für Biomedizinische Technik im VDE - BMT 2010, 2010, Rostock, Germany

S. Biederer, T.F. Sattel, S. Kren, M. Erbe, T.Knopp, K. Lüdtke-Buzug, T.M. Buzug: A Spectrometer Using Oscillating and Static Fields to Measure the Suitability of Super-Paramagnetic Nanoparticles for Magnetic Particle Imaging, to be published in: World Molecular Imaging Congress, 2010, Kyoto, Japan

K. Lüdtke-Buzug, S. Biederer, T. M. Buzug: Analyse des Separationsergebnisses bei der Herstellung Superparamagnetischer Eisenoxid-Nanopartikel für Magnetic Particle Imaging, 44. Jahrestagung der Deutschen Gesellschaft für Biomedizinische Technik im VDE - BMT 2010, 2010, Rostock, Germany

D. Schneider, D. Rapoport, K. Lüdtke-Buzug: Monitoring adult stem cell response on superparamagnetic iron oxide nanoparticles for cancer therapy, 5th Annual Meeting of the German Society for Stem Cell Research (GSZ), 2010, Lübeck, Germany

T. F. Sattel, S. Biederer, T. Knopp, T. M. Buzug: Magnetic Field Generation For Multi-Dimensional Single-Sided Magnetic Particle Imaging, Proceedings of the International Society for Magnetic Resonance in Medicine, 2010, Mai, Stockholm, 18, p.3297

S. Biederer, T. Knopp, T. F. Sattel, M. Erbe, T. M. Buzug: Improved Estimation of the Magnetic Nanoparticle Diameter with a Magnetic Particle Spectrometer and Combined Fields, Proceedings of the International Society for Magnetic Resonance in Medicine, 2010, Mai, Stockholm, 18, p.954

T. F. Sattel, T. Knopp, S. Biederer, T. M. Buzug: Open Coil Arrangement for Interventional Magnetic Particle Imagin, Proceedings of the International Society for Magnetic Resonance in Medicine, 2010, Mai, Stockholm, 18, p.945

I. Graesslin, C. Steiding, B. Annighoefer, J. Weller, S. Biederer, D. Brunner, H. Homann, F. Schweser, U. Katscher, K. Pruessmann, P. Boernert: Local SAR Constrained Hotspot Reduction by Temporal Averaging, Proceedings of the International Society for Magnetic Resonance in Medicine, 2010, Mai, Stockholm, 18, p.4932

S. Biederer, T. F. Sattel, T. Knopp, M. Erbe, T. M. Buzug: Improving the Imaging Quality in Magnetic Particle Imaging by a Traveling Phase Trajectory, Proceedings of the International Society for Magnetic Resonance in Medicine, 2010, Mai, Stockholm, 18, p.3296

I. Graesslin, S. Wang, S. Biederer, G. Mens, B. Annighoefer, H. Homann, J. Duyn, P. Harvey: Towards Patient-Specific SAR Calculation for Parallel Transmission Systems, Proceedings of the International Society for Magnetic Resonance in Medicine, 2010, Mai, Stockholm, 18, p.3873

T. Knopp, M. Erbe, T. F. Sattel, S. Biederer, T. M. Buzug: Efficient Generation of a Magnetic Field-Free Line, Proceedings of the International Society for Magnetic Resonance in Medicine, 2010, Mai, Stockholm, 18, p.952

S. Kaufmann, S. Biederer, T.F. Sattel, T. Knopp, T.M. Buzug: A Surveillance Unit for Magnetic Particle Imaging, International Workshop on Magnetic Particle Imaging BoA, 2010, 1, p.9

K. Lüdtke-Buzug, S. Biederer, M. Erbe, T. Knopp, T.F. Sattel, T.M. Buzug: Superparamagnetic Iron Oxide Nanoparticles for Magnetic Particle Imaging, International Workshop on Magnetic Particle Imaging BoA, 2010, 1, p.2

F.M. Vogt, J. Barkhausen, S. Biederer, T.F. Sattel T. Knopp, K. Lüdtke-Buzug, T.M. Buzug: Current Iron Oxide Nanoparticles - Impact on MRI and MPI, International Workshop on Magnetic Particle Imaging BoA, 2010, 1, p.12

T.F. Sattel, T. Knopp, S. Biederer, M. Erbe, K. Lüdtke-Buzug, T.M. Buzug: Resolution Distribution in Single-Sided Magnetic Particle Imaging, International Workshop on Magnetic Particle Imaging BoA, 2010, 1, p.24

T. Knopp, S. Biederer, T.F. Sattel, K. Lüdtke-Buzug, M. Erbe, T.M. Buzug: Efficient Field-Free Line Generation for Magnetic Particle Imaging, International Workshop on Magnetic Particle Imaging BoA, 2010, 1, p.26

D. Finas, B. Ruhland, K. Baumann, T. Knopp, T.F. Sattel, S. Biederer, K. Lüdtke-Buzug, T.M. Buzug, K. Diedrich: Sentinal Lymphnode Detection in Breast Cancer by Magnetic Particle Imaging Using Superparamagnetic Nanoparticles, International Workshop on Magnetic Particle Imaging BoA, 2010, 1, p.35

S. Biederer, T.F. Sattel, T. Knopp, M. Erbe, K. Lüdtke-Buzug, F.M. Vogt, J. Barkhausen, T.M. Buzug: A Spectrometer to Measure the Usability of Nanoparticles for Magnetic Particle Imaging, International Workshop on Magnetic Particle Imaging BoA, 2010, 1, p.20

T. Knopp, S. Biederer, T. F. Sattel, J. Weizenecker, B. Gleich, J. Borgert, T. M. Buzug: Rekonstruktion von Magnetic Particle Imaging Daten mittels einer modellierten Systemfunktion, Bildverarbeitung für die Medizin, 2010, Aachen, Springer, p.1-5

S. Biederer, T. F. Sattel, T. Knopp, T. M. Buzug: Variable Trajektoriendichte in Magnetic Particle Imaging, Bildverarbeitung für die Medizin, 2010, Aachen, Springer, p.6-10

T. Knopp, T. F. Sattel, S. Biederer, T. M. Buzug: Limitations of Measurement-Based System Functions in Magnetic Particle Imaging, SPIE Medical Imaging, 2010

S. Biederer, T. F. Sattel, T. Knopp, K. Lüdtke-Buzug, B. Gleich, J. Weizenecker, J. Borgert, T. M. Buzug: The Influence of the Particle-Size Distribution on the Image Resolution in Magnetic Particle Imaging, Magnetic Resonance Materials in Physics, Biology and Medicine, 2009, October, Antalya, 22, p.499

S. Biederer, F. M. Vogt, K. Lüdtke-Buzug, T. Knopp, T. F. Sattel, J. Barkhausen, T. M. Buzug: A Study on the Performance of Different Superparamagnetic Iron Oxide Particles in Magnetic Particle Imaging, Magnetic Resonance Materials in Physics, Biology and Medicine, 2009, October, Antalya, 22, p.709

B. Ruhland, K. Baumann, T. Knopp, T. F. Sattel, S. Biederer, K. Lüdtke-Buzug, T. M. Buzug, K. Diedrich, D. Finas: Magnetic Particle Imaging durch Superparamagnetische Nanopartikel zur Sentinellymphknotendetektion beim Mammakarzinom, Geburtshilfe und Frauenheilkunde, 2009, 69, p.758

T. F. Sattel, S. Biederer, T. Knopp, K. Lüdtke-Buzug, B. Gleich, J. Borgert, T. M. Buzug: Hand-Held Concept of a Magnetic Particle Imaging Device, Suppl Mol Imaging Biol, 2009, 11, p.J521

K. Lüdtke-Buzug, S. Biederer, T. F. Sattel, T. Knopp, T. M. Buzug: Synthesis and Spectroscopic Analysis of Super-Paramagnetic Nanoparticles for Magnetic Particle Imaging, Suppl Mol Imaging Biol, 2009, 11, p.J054

S. Biederer, T. Knopp, T. F. Sattel, K. Lüdtke-Buzug, B. Gleich, J. Weizenecker, J. Borgert, T. M. Buzug: Estimation of Magnetic Nanoparticle Diameter with a Magnetic Particle Spectrometer, World Congress on Medical Physics and Biomedical Engineering, Springer IFMBE Series, 2009, September, Munich, 25/VIII, p.61-64

K. Lüdtke-Buzug, S. Biederer, T. F. Sattel, T. Knopp, T. M. Buzug: Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging, World Congress on Medical Physics and Biomedical Engineering, Springer IFMBE Series, 2009, September, Munich, 25/VIII, p.226-229

T. F. Sattel, S. Biederer, T. Knopp, K. Lüdtke-Buzug, B. Gleich, J. Weizenecker, J. Borgert, T. M. Buzug: Single-Sided Coil Configuration for Magnetic Particle Imaging, World Congress on Medical Physics and Biomedical Engineering, Springer IFMBE Series, 2009, September, Munich, 25/VII, p.281-284

T. M. Buzug, S. Biederer, T. Knopp, T. F. Sattel, K. Lüdtke-Buzug: Magnetic Particle Imaging – Challenges and Promises of a new Modality, World Congress on Medical Physics and Biomedical Engineering, Springer IFMBE Series, 2009, September, Munich, 25/IV, p.1471-1474

T. Knopp, T. Sattel, S. Biederer, J. Weizenecker, B. Gleich, J. Borgert, T. M. Buzug: Trajektoriendichte bei Magnetic Particle Imaging, Bildverarbeitung für die Medizin, 2009, March, Heidelberg

T. Knopp, S. Biederer, T. Sattel, T. M. Buzug: Singular Value Analysis for Magnetic Particle Imaging, Proc. IEEE Nuc. Sci. Symp. Med. Im. Conf., 2008, p.4525-4529

S. Biederer, T. Sattel, T. Knopp, K. Lüdtke-Buzug, B. Gleich, J. Weizenecker, J. Borgert, T. M. Buzug: A Spectrometer for Magnetic Particle Imaging, Proc. 4th European Congress for Medical and Biomedical Engineering, Springer IFMBE Series, 2008, 22, p.2313-2316

K. Lüdtke-Buzug, S. Biederer, T. Sattel, T. Knopp, T. M. Buzug: Preparation and Characterization of Dextran-Covered Fe3O4 Nanoparticles for Magnetic Particle Imaging, Proc. 4th European Congress for Medical and Biomedical Engineering, Springer IFMBE Series, 2008, 22, p.2343-2346

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